Inspired by a comment on this question.
Some research basically re-examines some previous claim with slightly changed methods or in slightly changed conditions, acting on assumption that previous research missed some nuance and the results might differ with this update. Some of such articles even manage to successfully overturn previous assumptions; but some of them are just busywork that would be rejected by any competent peer review. Peer review is important in culling the weak. On the other hand it increases the publishing cycle length, and increases chances that you start working on a problem someone is already getting ready to publish researc on; that spawned a practice of distributing preprints - a way to tell other scientist "hey, I took this subject, if you start on it, you are competing with me". This practice was limited by its very nature - without centralised publishing, there were no way for these publications to reach significant notoriety outside of its respective field (or even within it) other than by word-of-mouth - in other words, it also passed through a kind of peer review; and efforts to increase this non-reviewed exchange of information tended to meet resistance from the scientific community.
But with advent of Internet, everything changed. Now preprints can easilybe published for everyone to see, and research related to high-profile events can just as easily make headlines of mainstream media bypassing any review by people who can actually understand what the authors are talking about.
What does it mean for this site? It means that "busywork research" I mentioned can't be shut down on the journal review stage, now it can be grabbed by sensation-hungry mainstream media off preprint sites (thus becoming notable) and spawn a stream of questions with only a slight change in claims, and with standard answers along the lines of "the research isn't sound and will be rejected during review for publishing".
Are questions with claims based on research articles that are yet to pass peer review notable enough for this site?